Key Nervous System Components Influence Gastrointestinal Tumour Growth
Researchers have found that common nervous system components are present in the gastrointestinal tract and influence tumour growth, revealing new opportunities for cancer treatment.
Our gut contains its own nervous system, often referred to as the "second brain". Neuropeptides, such as CGRP, play a key role in this system, relaying messages throughout the nervous system by connecting to receptors on the outside of cells.
- CGRP, a common neuropeptide, and its receptor RAMP1 have been found to influence tumour growth in colorectal and stomach cancers.
The gut's nervous system is a key player in influencing a variety of processes, including tumour growth.
The discovery by the team at the Olivia Newton-John Cancer Research Institute (ONJCRI) and La Trobe School of Cancer Medicine creates promising new avenues for treatment with existing approved therapies.
Author's summary: New research reveals nervous system components influence gastrointestinal tumour growth.
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