Demetri Maxim's life was affected by kidney disease at a young age, when his mother's kidneys stopped working.
She underwent dialysis and later received a kidney transplant, but Maxim inherited the disease, Polycystic Kidney Disease (PKD).
About one in seven Americans has Chronic Kidney Disease (CKD), with 10% of cases due to a genetic condition.
Maxim became determined to find a cure, and his "Aha!" moment came in 2021, when a study in Nature Magazine showed that PKD is reversible in mice using CRISPR technology.
PKD is reversible in mice using CRISPR technology.
Learn more about Biotech Nephrogen at TechCrunch Disrupt 2025.
Author's summary: Biotech Nephrogen uses AI and gene therapy to fight kidney disease.